Table 4—

Concordant and discordant tuberculin skin test(TST) ≥10 mm and interferon-γ release assay (IGRA) results depending on putative risk factors

TST/IGRAp-value
-/-+/--/++/+
n%n%n%n%
Age
 16–29 yrs13229.821247.9102.38920.1
 30–39 yrs9026.814643.561.89428.0
 40–49 yrs3717.58841.520.98540.1
 50–59 yrs2211.17839.252.59447.2
 ≥60 yrs828.6828.6310.7932.1<0.001
Sex
 Female20923.839144.5171.926129.7
 Male8023.514141.592.611032.40.644
BCG vaccination
 Only at birth7319.713135.4102.715642.2
 1 additional10324.218643.7102.312729.8
 2 additional7825.914949.551.76922.9
 3–10 additional3528.96654.510.81915.7<0.001
Years since last BCG
 >15 yrs19220.937340.5242.633136.0
 >10–15 yrs7231.711952.410.43515.4
 1–10 years2535.24056.311.457.0<0.001
Profession
 Administrator3518.87640.942.27138.2
 Auxiliaries, cleaning staff4725.06534.642.17238.3
 Technicians (radiology, lab, etc.)1922.44451.833.51922.4
 Nurses#13424.527650.471.313123.9
 Physicians#5425.67133.683.87837.0<0.001
Risk assessment
 Low risk3117.96939.963.56738.7
 Moderate risk8721.417743.561.513733.7
 High risk17126.828644.8142.216726.20.006
Time working in healthcare
 Start of work8239.48339.921.04119.7
 <5 yrs7926.214247.2103.37023.3
 5–<10 yrs5224.510248.162.85224.5
 10–<15 yrs2517.66545.810.75135.9
 15–<20 yrs1516.73640.011.13842.2
 ≥20 yrs3613.610439.262.311944.9<0.001
  • BCG: bacillus Calmette–Guérin. #: repeated TST during study period: nurses (30.5%) physicians (14.7%), p-value <0.0005.