Measurement | Midazolam/ hydrocodone | Propofol | p-value |
Subjects n | 100 | 100 | |
Baseline | |||
Systolic BP mmHg | 138±22 | 134±24 | 0.105 |
Diastolic BP mmHg | 79±17 | 80±15 | 0.713 |
Cardiac frequency beats·min−1 | 83±14 | 83±16 | 0.816 |
Initial | |||
Systolic BP mmHg | 133±26 | 128±23 | 0.060 |
Diastolic BP mmHg | 80±16 | 78±16 | 0.192 |
Cardiac frequency beats·min−1 | 88±15 | 83±15 | 0.040 |
Final | |||
Systolic BP mmHg | 135±24 | 125±26 | 0.002 |
Diastolic BP mmHg | 78±15 | 73±23 | 0.098 |
Cardiac frequency beats·min−1 | 91±16 | 87±15 | 0.013 |
Re-evaluation after 1 h | |||
Systolic BP mmHg | 122±20 | 122±22 | 0.832 |
Diastolic BP mmHg | 71±14 | 71±17 | 0.993 |
Cardiac frequency beats·min−1 | 90±14 | 85±17 | 0.040 |
Re-evaluation after 2 h | |||
Systolic BP mmHg | 131±20 | 129±18 | 0.906 |
Diastolic BP mmHg | 78±11 | 76±11 | 0.288 |
Cardiac frequency beats·min−1 | 84±13 | 83±14 | 0.469 |
Data are presented as mean±sd, unless otherwise indicated. BP: blood pressure. Values in bold show statistical significance.