Diagnostic accuracy of individual pleural fluid tests for identifying parapneumonic effusions
| Sensitivity | Specificity | LR+ | LR- | AUC | |
| CRP ≥80 mg·L−1 | 49 (41–57) | 93 (89–98) | 7.4 (4–13.8) | 0.54 (0.46–0.64) | 0.83 (0.78–0.87) |
| sTREM-1 ≥80 pg·mL−1 | 73 (66–81) | 72 (64–79) | 2.6 (2–3.4) | 0.37 (0.28–0.49) | 0.79 (0.74–0.84) |
| PCT ≥0.25 ng·mL−1 | 52 (43–60) | 73 (64–81) | 1.9 (1.4–2.6) | 0.66 (0.54–0.81) | 0.63 (0.56–0.70) |
| LBP ≥17 μg·mL−1 | 49 (40–57) | 90 (84–95) | 4.7 (2.8–7.8) | 0.57 (0.49–0.68) | 0.80 (0.75–0.85) |
Data are presented as % (95% CI). LR+: likelihood ratio positive; LR-: likelihood ratio negative; AUC: area under curve; CRP: C-reactive protein; sTREM-1: soluble triggering receptor expressed on myeloid cells; PCT: procalcitonin; LPB: lipopolysaccharide-binding protein.