Table 3—

Diagnostic accuracy of individual pleural fluid tests for identifying tuberculous as compared with malignant effusions

SensitivitySpecificityLR+LR-AUC
CRP ≥20 mg·L−174 (61–87)77 (63–92)3.3 (1.8–6)0.34 (0.20–0.55)0.81 (0.72–0.90)
sTREM-1 ≥80 pg·mL−162 (47–76)85 (73–97)4.1 (1.9–8.9)0.45 (0.31–0.65)0.83 (0.74–0.92)
PCT ≥0.25 ng·mL−125 (12–39)76 (60–91)1 (0.5–2.2)0.98 (0.77–1.26)0.52 (0.39–0.65)
LBP ≥7 μg·mL−179 (67–92)77 (63–92)3.5 (1.9–6.4)0.27 (0.15–0.48)0.83 (0.74–0.92)
  • Data are presented as % (95% CI). LR+: likelihood ratio positive; LR-: likelihood ratio negative; AUC: area under curve; CRP: C-reactive protein; sTREM-1: soluble triggering receptor expressed on myeloid cells; PCT: procalcitonin; LPB: lipopolysaccharide-binding protein.