Table 4—

Univariate analysis relating survival to selected baseline variables

VariablesHazard ratio95% CIp-value
Age yrs1.040.97–1.110.297
NYHA class (II–III/IV)2.250.86–5.870.096
DL,CO % pred0.930.87–1.000.049
KCO % pred0.940.88–1.010.071
Pa,O2 kPa0.800.35–1.840.604
6MWD m0.990.99–1.000.157
Sa,O2 6MWD %0.970.91–1.040.444
fC beats·min−11.071.01–1.120.010
Pra mmHg0.990.84–1.170.904
Mean Ppa mmHg1.071.00–1.140.049
CI L·min−1·m−20.230.05–1.020.054
PVR dyn·s·cm−51.011.00–1.010.002
SV,O2 %1.020.95–1.100.513
Medical treatment of PH (yes/no)1.320.39–4.930.656
  • A value of hazard ratio >1 indicates an increased risk of death. NYHA: New York Heart Association; DL,CO: diffusing capacity of the lung for carbon monoxide; % pred; % predicted; KCO: transfer factor of the lung for carbon monoxide; Pa,O2: arterial oxygen tension; 6MWD: 6-min walk distance; Sa,O2: arterial oxygen saturation; fC: cardiac frequency; Pra: right atrial pressure; Ppa: pulmonary arterial pressure; CI: cardiac index; PVR: pulmonary vascular resistance; SV,O2: venous oxygen saturation; PH: pulmonary hypertension.