Table 3—

Distribution of theCYP1B1 Asn453Ser (453 N/S) genotypes according to familial pulmonary arterial hypertension phenotype: affected (AMCs) and unaffected BMPR2 mutation carriers (UMCs)

AMCUMCp-value
Females
 N/N46 (74)10 (42)0.005
 N/S or S/S16 (26)14 (58)
 Total62 (100)24 (100)
Males
 N/N18 (60)17 (71)0.407
 N/S or S/S12 (40)7 (29)
 Total30 (100)24 (100)
  • Data are presented as n (%), unless otherwise stated.