Definition of inadequate response to pulmonary arterial hypertension(PAH) treatments (see also section 7.2.5 and 7.2.6)
| Inadequate clinical response for patients who were initially in WHO-FC II or III: |
| (1) Resulting clinical status defined as stable and not satisfactory |
| (2) Resulting clinical status defined as unstable and deteriorating |
| Inadequate clinical response for patients who were initially in WHO-FC IV: |
| (1) No rapid improvement to WHO-FC III or better |
| (2) Resulting clinical status defined as stable and not satisfactory |
WHO-FC: World Health Organization functional class.