Association of cannabis use with lung function at age 32 yrs amongst non-tobacco smokers
| Subjects n | Coefficient | 95% CI | p-value | |
| FEV1 mL | 449 | 1.5 | -16.0–19.0 | 0.867 |
| FVC mL | 449 | 17.5 | -2.5–37.4 | 0.087 |
| FEV1/FVC % | 449 | -0.19 | -0.42–0.04 | 0.100 |
| TLC mL | 433 | 33.5 | 9.9–57.1 | 0.006 |
| FRC mL | 434 | 8.1 | -13.1–29.4 | 0.452 |
| RV mL | 433 | 12.0 | -0.3–24.4 | 0.057 |
| Raw cmH2O·L−1·s−1 | 434 | 0.029 | 0.001–0.057 | 0.042 |
| sGaw mL·s−1·cmH2O−1·L−1 | 434 | -6.7 | -11.8– -1.7 | 0.010 |
| TL,CO mL·min−1·mmHg−1 | 418 | 0.032 | -0.114–0.178 | 0.662 |
| TL,CO/VA mL·min−1·mmHg−1·L−1 | 418 | -0.019 | -0.042–0.004 | 0.106 |
| VA mL | 438 | 28.5 | 4.3–52.7 | 0.021 |
FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume; Raw: airway resistance; sGaw: specific airway conductance; TL,CO: transfer factor of the lung for carbon monoxide; VA: alveolar volume. Linear regression analyses of lung function at age 32 yrs using cannabis exposure as the predictor. Analyses are restricted to those without a tobacco smoking history. All analyses adjusted for sex and, except for FEV1/FVC and sGaw, for height. Analyses of TL,CO also adjust for exhaled carbon monoxide and blood haemoglobin. Coefficients represent the difference in lung function associated with each joint-year of cannabis up to age 32 yrs.