Treatment differences
| Outcome | Twice daily physiotherapy | No regular physiotherapy | p-value |
| Total LCQ score improvement | 1.3 (-0.17–3.25) | 0 (-1.5–0.5) | 0.002 |
| 24-h sputum volume mL | 2 (0–6) | -1 (-5–0) | 0.02 |
| FEV1 L | -0.01 (-0.06–0.08) | -0.01 (-0.1–0.11) | 0.7 |
| FVC L | -0.01 (-0.09–0.28) | 0.06 (-0.08–0.21) | 0.9 |
| FEF25–75% L·s−1 | -0.02 (-0.17–0.16) | 0.04 (-0.1–0.34) | 0.6 |
| MIP cmH2O | -1 (-9–7) | 5.5 (-10–12.5) | 0.7 |
| MEP cmH2O | 5 (-11–25) | 8.5 (-3.7–19.7) | 0.7 |
| Exercise capacity m | 40 (15–80) | 0 (-10–20) | 0.001 |
| Sputum bacterial load cfu·mL−1 | -1×103 (-2.78×106–1.74×107) | 1×103 (-6.5×107–6.4×106) | 0.72 |
| Total SGRQ score improvement | 7.8 (-0.99–14.5) | -0.7 (-2.3–0.05) | 0.005 |
| Exacerbations n | 5 | 7 | 0.48 |
Data are presented as median (interquartile range), unless otherwise stated. LCQ: Leicester Cough Questionnaire; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75: forced expiratory flow at 25–75% of FVC; MIP: maximum inspiratory pressure; MEP: maximum expiratory pressure; SGRQ: St George’s Respiratory Questionnaire.