Suggested assessments and timing for the follow-up of patients with pulmonary arterial hypertension
| At baseline (prior to therapy) | Every 3–6 months# | 3–6 months after initiation or changes in therapy | In case of clinical worsening | |
| Clinical assessment WHO-FC ECG | ✓ | ✓ | ✓ | ✓ |
| 6-MWT¶ | ✓ | ✓ | ✓ | ✓ |
| Cardiopulmonary exercise testing¶ | ✓ | ✓ | ✓ | |
| BNP/NT-proBNP | ✓ | ✓ | ✓ | ✓ |
| Echocardiography | ✓ | ✓ | ✓ | |
| RHC | ✓+ | ✓§ | ✓§ |
WHO-FC: World Health Organization functional class; ✓: assessment is suggested; 6-MWT: 6-min walking test; BNP: brain natriuretic peptide; NT-proBNP: N-terminal proBNP; RHC: right heart catheterisation. #: intervals should to be adjusted to individual patients needs; ¶: usually one of the two exercise tests is performed; +: is recommended (table 11A); §: should be performed (table 11A).