Univariate Cox proportional hazard analysis
Parameters | RR (95% CI)# | p-value |
Male sex | 1.96 (0.92–4.20) | 0.082 |
Age | 1.06 (1.02–1.09) | 0.001 |
Smoker | 1.78 (0.87–3.63) | 0.120 |
PSA | 2.33 (1.04–5.18) | 0.039 |
CT criteria | ||
Bx extent | 1.04 (1.02–1.05) | <0.0005 |
Dilatation severity | 1.03 (1.01–1.04) | <0.0005 |
Wall thickness | 1.07 (1.04–1.10) | <0.0005 |
Small airway plugging | 0.506 | |
Large airway plugging | 1.04 (1.02–1.07) | 0.002 |
Mosaicism | 1.03 (1.00–1.06) | 0.049 |
Emphysema | 1.05 (1.02–1.08) | 0.001 |
LF criteria % pred | ||
FEV1 | 0.97 (0.95–0.98) | <0.0005 |
FVC | 0.98 (0.96–0.99) | 0.003 |
FEV1/FVC | 0.209 | |
RV | 0.176 | |
TLC | 0.98 (0.96–1.01) | 0.192 |
RV/TLC | 1.01 (1.00–1.02) | 0.021 |
TL,CO | 0.95 (0.93–0.97) | <0.0005 |
KCO | 0.98 (0.97–0.99) | 0.007 |
Health-related quality of life questionnaire scores | ||
Fatigue | 1.14 (0.97–1.35) | 0.122 |
MRC wheeze | 1.26 (0.92–1.71) | 0.147 |
MRC dyspnoea | 2.89 (1.84–4.54) | <0.0005 |
SGRQ total | 1.04 (1.01–1.06) | 0.002 |
SGRQ symptoms | 1.02 (1.00–1.04) | 0.121 |
SGRQ activities | 1.04 (1.02–1.06) | <0.0005 |
SGRQ impacts | 1.02 (1.00–1.04) | 0.035 |
RR: relative rate; CI: confidence interval; PSA: Pseudomonas aeruginosa; CT: computed tomography; Bx: bronchiectasis; LF: lung function; % pred: % predicted; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; RV: residual volume; TLC: total lung capacity; TL,CO: transfer factor of the lung for carbon monoxide; KCO: transfer coefficient of the lung for carbon monoxide; MRC: Medical Research Council; SGRQ: St George’s Respiratory Questionnaire. #: RR >1 describes a positive correlation between the parameter and mortality, whereas RR <1 suggests a negative correlation. Entries in bold are statistically significant.