Table 2—

Univariate Cox proportional hazard analysis

ParametersRR (95% CI)#p-value
Male sex1.96 (0.92–4.20)0.082
Age1.06 (1.02–1.09)0.001
Smoker1.78 (0.87–3.63)0.120
PSA2.33 (1.04–5.18)0.039
CT criteria
 Bx extent1.04 (1.02–1.05)<0.0005
 Dilatation severity1.03 (1.01–1.04)<0.0005
 Wall thickness1.07 (1.04–1.10)<0.0005
 Small airway plugging0.506
 Large airway plugging1.04 (1.02–1.07)0.002
 Mosaicism1.03 (1.00–1.06)0.049
 Emphysema1.05 (1.02–1.08)0.001
LF criteria % pred
 FEV10.97 (0.95–0.98)<0.0005
 FVC0.98 (0.96–0.99)0.003
 TLC0.98 (0.96–1.01)0.192
 RV/TLC1.01 (1.00–1.02)0.021
TL,CO0.95 (0.93–0.97)<0.0005
KCO0.98 (0.97–0.99)0.007
Health-related quality of life questionnaire scores
 Fatigue1.14 (0.97–1.35)0.122
 MRC wheeze1.26 (0.92–1.71)0.147
 MRC dyspnoea2.89 (1.84–4.54)<0.0005
 SGRQ total1.04 (1.01–1.06)0.002
 SGRQ symptoms1.02 (1.00–1.04)0.121
 SGRQ activities1.04 (1.02–1.06)<0.0005
 SGRQ impacts1.02 (1.00–1.04)0.035
  • RR: relative rate; CI: confidence interval; PSA: Pseudomonas aeruginosa; CT: computed tomography; Bx: bronchiectasis; LF: lung function; % pred: % predicted; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; RV: residual volume; TLC: total lung capacity; TL,CO: transfer factor of the lung for carbon monoxide; KCO: transfer coefficient of the lung for carbon monoxide; MRC: Medical Research Council; SGRQ: St George’s Respiratory Questionnaire. #: RR >1 describes a positive correlation between the parameter and mortality, whereas RR <1 suggests a negative correlation. Entries in bold are statistically significant.