Table 3—

Association of individualCTLA4 single nucleotide polymorphisms (SNPs) with chronic bronchitis phenotype in the International Chronic obstructive pulmonary disease Genetics Network (ICGN) family study and chronic obstructive pulmonary disease cases of the Bergen study

SNP IDSNP nameICGN family studyBergen study
Risk alleleInformative families np-valueRisk alleleEffect estimatesp-value
1rs926169T1650.0432T0.956 (0.412–1.843)0.9365
2rs733618A600.6879A0.951 (0.634–1.442)0.8143
3rs11571316C1760.0230T0.799 (0.649–0.983)0.0359
4rs16840252T1000.4015T0.983 (0.762–1.269)0.8669
5rs231775G1630.0081G1.247 (1.019–1.526)0.0325
6rs231777T910.7428T0.886 (0.674–1.166)0.3791
7rs231779C1620.0112C1.221 (0.998–1.496)0.0532
8rs3087243G1750.0079G0.805 (0.654–0.991)0.0408
9rs231725G1520.0181G1.229 (1.002–1.508)0.0401
  • Data are presented as OR (95% CI), unless otherwise indicated.