Patterns of variables of subjects with full data set# defined by the diana method
| Cluster | ||||
| 1 | 2 | 3 | 4 | |
| Pre-BD FEV1/FVC % | -- | - | +/- | +/- |
| Pre-BD FEV1 % pred | -- | -- | +/- | +/- |
| Reversibility % | + + | +/- | - | +/- |
| DL,CO/VA¶ % pred | -- | -- | +/- | +/- |
| FRC % pred | + + | + | +/- | +/- |
| Log IgE g·L−1 | + + | -- | +/- | +/- |
| FeNO ppb | + | -- | +/- | +/- |
| Sputum production % | 100 | 0 | 0 | 100 |
| Smoking history pack-yrs | + + | + + | -- | +/- |
BD: bronchodilator; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; % pred: % predicted; DL,CO: diffusing capacity of the lung for carbon monoxide; VA: alveolar volume; FRC: functional residual capacity; Ig: immunoglobulin; FeNO: exhaled nitric oxide fraction. --: ≥20% below mean; -: ≥10% and <20% below mean; +/-: within 10% of mean; +: ≥10% and <20% above mean; ++: ≥20% above mean. #: n = 175; ¶: adjusted for haemoglobin concentration.