Table 2—

Characteristics of clusters of subjects with full data set# defined by the agnes method

Subjects n1514307838
Pre-BD FEV1/FVC %54.7±10.456.4±9.265.5±9.170.1±7.070.5±8.9
Pre-BD FEV1 % pred58.0±15.560.2±18.481.0±19.187.0±14.181.1±15.3
Reversibility %17.1±15.26.7±6.711.7±10.56.1±5.08.9±8.6
DL,CO/VA+ % pred75.4±10.776.5±13.2100.3±10.6100.4±13.398.5±13.2
FRC % pred132.7±28.1120.6±34.4108.2±18.4103.2±20.7101.6±19.2
Log IgE g·L−15.3±1.43.1±1.05.3±1.24.1±1.44.0±1.7
FeNO ppb33.1±35.623.7±11.469.2±26.122.6±10.531.6±23.9
Sputum production n (%)15 (100)0 (0)0 (0)0 (0)38 (100)
Smoking history pack-yrs36.3±22.938.1±31.52.6±7.15.8±10.67.4±10.4
  • Data are presented as mean±sd, unless otherwise indicated. BD: bronchodilator; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; % pred: % predicted; DL,CO: diffusing capacity of the lung for carbon monoxide; VA: alveolar volume; FRC: functional residual capacity; Ig: immunoglobulin; FeNO: exhaled nitric oxide fraction. #: n = 175; : listed in order of pre-BD FEV1/FVC; +: adjusted for haemoglobin concentration.