Table 1—

Patient characteristics

CharacteristicBronchiectasisp-value
SevereModerateMild
Subjects n512940
Male25 (49)10 (34.5)16 (40)0.4
Age yrs68 (60–74)69.5 (56.2–77.2)67 (59–76.7)0.9
Ex-smokers18 (35)9 (31)15 (37.5)0.9
Pack-yr history0 (0–8)0 (0–2.5)0 (0–7)0.7
FEV1 L1.55 (1.30–2.15)1.8 (1.34–2.47)2.3 (1.9–2.7)0.002
FEV1 % pred69 (47–86)78.2 (69.7–89.6)82.5 (71.5–96)0.006
FVC L2.45 (1.80–3.20)2.55 (2–3.19)3.06 (2.5–3.5)0.04
FVC % pred77(61–93)85.9 (85–100)90 (78.5–106)0.01
FEV1/FVC ratio0.68 (0.58–0.77)0.76 (0.65–0.85)0.74 (0.66–0.82)0.01
FEV1/FVC % pred89 (73–97)94 (85–105)94.9 (86–102)0.09
Purulent sputum when stable %100140<0.0001
Chronically colonised %10058.60<0.0001
Chronically colonised with Pseudomonas aeruginosa %51.047.00<0.0001
Cystic bronchiectasis on CT scan %62.710.30<0.0001
Lobes affected5 (4–6)4 (1.5–5)2 (1–3)<0.0001
Outpatient exacerbations in the preceding 12 months3 (1.75–5.25)1 (0–3)0 (0–1.25)<0.0001
  • Data are presented as n (%) or median (interquartile range), unless otherwise stated. FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; CT: computed tomography.