Table 3—

ORs and 95% CIs of high level of high-sensitivity C-reactive protein (hs-CRP; >3 mg) in subjects of the Swiss study on Air Pollution and Lung Diseases in Adults (SAPALDIA)

MalesFemales
Total subjectsUnadjustedModel 1#Model 2#,¶Total subjectsUnadjustedModel 1+Model 2¶,+
Subjects n261625952595286325822582
FEV1 decline
 Non-fast2016 (11.7)Ref.Ref.Ref.2121 (16.4)Ref.Ref.Ref.
 Fast600 (19.5)1.83 (1.44–2.34)1.25 (0.96–1.63)1.38 (1.05–1.79)742 (25.9)1.78 (1.44–2.34)1.31 (1.05–1.65)1.42 (1.13–1.77)
Weight change
 Lost410 (9.3)0.73 (0.48–1.10)0.62 (0.41–0.96)457 (12.7)1.28 (0.87–1.89)1.22 (0.81–1.84)
 Gained ≤5%644 (12.3)Ref.Ref.569 (10.2)Ref.Ref.
 Gained ≤9%556 (13.3)1.10 (0.78–1.54)1.20 (0.85–1.72)578 (16.8)1.78 (1.25–2.51)1.74 (1.20–2.52)
 Gained ≤14%530 (14.2)1.18 (0.84–1.65)1.44 (1.01–2.06)560 (19.3)2.11 (1.49–2.97)2.24 (1.56–3.23)
 Gained >14%476 (18.1)1.58 (1.13–2.19)2.04 (1.42–2.93)699 (31.3)4.02 (2.93–5.51)4.51 (3.21–6.34)
  • Data are presented as n (% with high CRP) or OR (95% CI), unless otherwise indicated. FEV1: forced expiratory volume in 1 s; Ref.: reference category. #: adjusted for age, age squared, fast FEV1 decline, categories of weight change, smoking status, lifetime smoking (pack-yrs), physical activity, diabetes and study area (random effect); : no adjustment for weight change categories; +: adjusted for age, age squared, fast FEV1 decline, categories of weight change, smoking status, lifetime smoking (pack-yrs), physical activity, diabetes, hormone replacement therapy and study area (random effect).