Table 2—

Age-adjusted high-sensitivity C-reactive protein (hs-CRP) concentration (mg·L−1) for non-fast and fast forced expiratory volume in 1 s (FEV1) decliners

MalesFemales
Non-fast FEV1 declinersFast FEV1 declinersp-value#Non-fast FEV1 declinersFast FEV1 declinersp-value#
Subjects n20166002121742
Unstratified by body weight change categories0.91 (0.87–0.95)1.22 (1.13–1.31)<0.0011.00 (0.96–1.04)1.24 (1.15–1.33)<0.001
Weight change categories
 Lost0.77 (0.69–0.85)1.02 (0.83–1.27)0.0170.68 (0.61–0.76)0.83 (0.67–1.02)0.121
 Gained ≤5%0.78 (0.72–0.85)1.07 (0.92–1.25)<0.0010.79 (0.73–0.87)0.90 (0.77–1.04)0.174
 Gained ≤9%0.82 (0.75–0.89)1.10 (0.93–1.31)0.0020.87 (0.80–0.96)1.00 (0.84–1.20)0.169
 Gained ≤14%1.08 (0.98–1.18)1.16 (1.00–1.35)0.4231.14 (1.04–1.26)1.30 (1.12–1.52)0.161
 Gained >14%1.25 (1.12–1.40)1.60 (1.36–1.87)0.0151.59 (1.46–1.73)1.98 (1.74–2.26)0.005
 Interaction0.362§0.989§
Smoking status
 Current smoker1.12 (1.03–1.22)1.55 (1.35–1.79)<0.0010.96 (0.87–1.06)1.36 (1.18–1.58)<0.001
 Never-smoker0.78 (0.73–0.83)1.05 (0.92–1.20)<0.0011.01 (0.96–1.07)1.06 (0.96–1.19)0.435
 Interaction0.710§<0.001§
Physical activity
 Adequately active+0.82 (0.77–0.88)1.10 (1.01–1.21)<0.0010.90 (0.84–0.98)1.12 (1.01–1.23)<0.001
 Inadequately active0.95 (0.91–1.00)1.27 (1.17–1.38)<0.0011.03 (0.98–1.08)1.28 (1.18–1.38)<0.001
 Interaction0.486§0.427§
Hormonal replacement therapy0.95 (0.90–1.00)1.17 (1.08–1.26)<0.001
 No therapy1.23 (1.12–1.35)1.52 (1.35–1.70)<0.001
 Interaction0.301§
  • Data are presented as geometric mean (95% CI), unless otherwise indicated. #: from linear regression models adjusting for age, unless otherwise stated; : 2002 data; +: exercise ≥2–3 times per week and sweaty or breathless for ≥1 h·week−1; §: p-value for interaction with fast FEV1 decline category (Wald test).