Logistic regression analyses with fast/slow tertile of decline in forced expiratory volume in 1 s (FEV1) as the dependent variable#
Stepwise logistic regression | Adjusted logistic regression¶ | ||||
OR (95% CI) | p-value+ | OR (95% CI) | p-value+ | ||
SF-36 physical score | 1.102 (1.030–1.180) | 0.005 | 1.080 (1.004–1.161) | 0.039 | |
Exacerbation rate | 2.760 (1.245–6.119) | 0.012 | 2.725 (1.184–6.271) | 0.018 | |
BDR§ | 4.316 (1.300–14.334) | 0.017 | 3.997 (1.083–14.748) | 0.038 | |
BMI kg·m−2 | 0.818 (0.680–0.984) | 0.033 | 0.775 (0.620–0.968) | 0.025 | |
Female sex | 0.445 (0.108–1.839) | 0.264 | |||
Age yrs | 1.005 (0.925–1.091) | 0.913 | |||
Smoking pack-yrs | 1.002 (0.958–1.047) | 0.935 | |||
FEV1 % pred | 1.016 (0.990–1.044) | 0.232 |
Odds ratios (ORs) relate to the odds of being in the fast tertile. CI: confidence interval; SF-36: 36-item short-form health survey; BDR: bronchodilator reversibility; BMI: body mass index; % pred: % predicted. #: all of the variables listed in table 1⇑ were available for inclusion in the stepwise model, and the variables listed were forced into the adjusted model; ¶: for sex, age, smoking and FEV1; +: significant values are shown in bold type; §: American Thoracic Society criteria.