Table 1—

Demographic data and indices values at study onset

TotalPatients seen at least twice
Subjects n4115934551
Age yrs41±1638±110.3941±1639±110.47
Male/female n195/21634/250.14219/12626/250.08
Nonatopic/atopic n61/3505/540.1943/3024/470.34
ACQ score1.5 (0–5.0)1.7 (0–5.3)0.341.7 (0–5.3)1.9 (0–5.3)0.34
ICS dose¶,+250 (0–2000)500 (0–2000)0.50250 (0–2000)500 (0–2000)0.37
FeNO ppb§33.7 (14.3–79.2)18.1 (6.9–47.5)<0.00134.8 (14.6–83.0)18.5 (6.1–55.5)<0.001
FEV1 % pred85.6±15.786.2±17.90.8085.0±20.686.5±18.00.79
  • Data are presented as mean±sd, median (range) (), or geometrical mean (geometrical interval) (§), unless otherwise indicated. ACQ: Asthma Control Questionnaire; ICS: inhaled corticosteroid; FeNO: exhaled nitric oxide fraction; FEV1: forced expiratory volume in 1 s; % pred: % predicted. #: comparison between nonsmoking and smoking group; +: ICS dose in μg equivalents beclomethasone diproprionate per day−1 with the exception of FeNO, nonsmoking and smoking groups were statistically similar.