UK500,001 | Placebo | |||
0.1 mg b.i.d. | 0.4 mg b.i.d. | 1.0 mg b.i.d. | ||
Trough | ||||
FEV6 L | -0.050 | -0.040 | -0.007 | -0.015 |
FVC L | -0.095 | -0.065 | -0.025 | -0.023 |
IC L | 0.070 | 0.012 | -0.012 | 0.020 |
Breathlessness score | 0.066 | 0.037 | -0.062 | 0.014 |
Cough score | 0.100 | -0.077 | -0.120 | 0.080 |
Sputum score | 0.023 | 0.126 | 0.038 | -0.006 |
FEV6: forced expiratory volume in six seconds; FVC: forced vital capacity; IC: inspiratory capacity.