Demographics, comorbidities, severity of the disease, clinical, laboratory and radiological findings on admission of the cancer population, according to the presence of neutropenia
| Characteristic | Group 2a | Group 2b | p-value |
| Demographics | |||
| Subjects n | 135 | 73 | |
| Male | 105 (78) | 51 (70) | 0.208 |
| Age mean±sd yrs | 71.3±12.8 | 68.3±14.6 | 0.126 |
| Age >65 yrs | 94 (70) | 44 (60) | 0.173 |
| Age >75 yrs | 53 (39) | 26 (36) | 0.605 |
| Comorbidities | |||
| Congestive heart failure | 30 (22) | 18 (25) | 0.691 |
| COPD | 47 (35) | 14 (19) | 0.018 |
| Diabetes mellitus | 26 (20) | 12 (16) | 0.582 |
| Cerebrovascular accident | 23 (17) | 4 (6) | 0.012 |
| Renal disease | 26 (19) | 11 (15) | 0.451 |
| Liver disease | 9 (6.7) | 1 (1.4) | 0.080 |
| Severity on admission | |||
| Altered mental status | 21 (16) | 5 (7) | 0.070 |
| Admission to ICU | 21 (16) | 9 (12) | 0.501 |
| MV on admission | 7 (5.2) | 4 (6.2) | 0.505 |
| Physical findings | |||
| Temperature <35 or ≥40°C | 6 (4.5) | 3 (4.2) | 0.615 |
| Respiratory rate ≥30 breaths·min−1 | 27 (20) | 13 (19) | 0.844 |
| Alteration of gas exchange# | 56 (42) | 29 (41) | 0.930 |
| Hypotension¶ | 11 (8.3) | 6 (8.2) | 0.990 |
| Heart rate ≥125 beats·min−1 | 20 (15) | 6 (11) | 0.458 |
| Laboratory values | |||
| Arterial pH<7.35 | 5 (3.7) | 1 (1.6) | 0.379 |
| Sodium <130 mmol·L−1 | 9 (6.7) | 11 (15.3) | 0.046 |
| Haematocrit <30% | 15 (11) | 29 (41) | 0.000 |
| BUN >30 mg·dL−1 | 27 (20) | 29 (40) | 0.002 |
| Radiology findings on CXR | |||
| Multilobar involvement | 36 (27) | 26 (36) | 0.178 |
| Pleural effusion | 32 (24) | 17 (23) | 0.946 |
| Cavitation | 3 (2.2) | 0 (0) | N/A |
| Medical treatment | |||
| ABT Compliant to local guidelines | 116 (88) | 51 (85) | 0.583 |
| Fluoroquinolone | 46 (34) | 34 (47) | 0.077 |
| β-lactam | 108 (80) | 49 (67) | 0.039 |
| Macrolide | 58 (43) | 29 (40) | 0.651 |
Data are presented as n (%), unless otherwise stated. Group 2a: community-acquired pneumonia (CAP) patients with solid cancer without neutropenia; Group 2b: CAP patients with functional or absolute neutropenia; COPD: chronic obstructive puImonary disease; ICU: intensive care unit; MV: mechanical ventilation; BUN: blood urea nitrogen; CXR: chest radiograph. #: arterial oxygen tension (Pa,O2) <60, Pa,O2/inspiratory oxygen fraction <300 or oxygen saturation <90%; ¶: systolic blood pressure <90 mmHg or diastolic blood pressure <60 mmHg.