Table 1—

Demographics, comorbidities, severity of the disease, clinical, laboratory and radiological findings of the study population on admission, according to the presence of cancer

CharacteristicGroup 1Group 2p-value
Demographics
 Subjects n2650310
 Male1604 (61)214 (69)0.004
 Age mean±sd yrs66.8±17.870.9±13.30.000
 Age >65 yrs1535 (58)215 (69)0.000
 Age >75 yrs1014 (38)126 (41)0.415
Comorbidities
 Congestive heart failure577 (22)55 (18)0.101
 COPD795 (30)90 (29)0.725
 Diabetes mellitus529 (20)55 (18)0.380
 Cerebrovascular accident436 (17)41 (13)0.144
 Renal disease301 (11)45 (15)0.102
 Liver disease95 (3.6)15 (4.8)0.269
Severity on admission
 Altered mental status349 (13)40 (13)0.895
 Admission to ICU322 (12)38 (12)0.924
 MV on admission83 (3.1)15 (5.0)0.092
Physical findings
 Temperature <35 or ≥40°C159 (6.0)11 (3.6)0.087
 Respiratory rate ≥30 breaths·min−1585 (22)59 (19)0.262
 Alteration of gas exchange#1,011(38)125 (41)0.406
 Hypotension148 (5.6)23 (7.5)0.180
 Heart rate ≥125 beats·min−1328 (12)33 (11)0.388
Laboratory values
 Arterial pH<7.35167 (6.3)11 (3.7)0.069
 Sodium <130 mmol·L−1156 (5.9)27 (8.7)0.049
 Haematocrit <30%131 (4.9)65 (21)0.000
 BUN >30 mg·dL−1535 (20)74 (24)0.108
Radiology findings on CXR
 Multilobar involvement714 (27)86 (28)0.765
 Pleural effusion479 (18)68 (22)0.098
 Cavitation28 (1.1)4 (1.3)0.435
  • Data are presented as n (%), unless otherwise stated. Group 1: community-acquired pneumonia (CAP) patients without cancer; Group 2: CAP patients with cancer; COPD: chronic obstructive pulmonary disease; ICU: intensive care unit; MV: mechanical ventilation; BUN: blood urea nitrogen; CXR: chest radiograph. #: arterial oxygen tension <60, Pa,O2/inspiratory oxygen fraction <300 or oxygen saturation <90%; : systolic blood pressure <90 mmHg or diastolic blood pressure <60 mmHg.