Pulmonary function and respiratory muscle strength test results following treatment with standard noninvasive ventilation(NIV) and autotitrating NIV compared with baseline
| Variable | Baseline | Standard NIV | Autotitrating NIV | Difference (95% CI) | p-value# |
| Subjects n | 20 | 20 | 20 | ||
| FVC L | 0.89±0.40 | 0.86±0.41¶ | 0.87±0.42¶ | 0.016 (-0.04–0.07) | 0.54 |
| FEV1 L | 0.66±0.31 | 0.62±0.30¶ | 0.62±0.32¶ | 0.002 (-0.04–0.04) | 0.93 |
| FEV1/FVC | 0.77±0.13 | 0.83±0.19¶ | 0.79±0.14¶ | -0.029 (-0.09–0.03) | 0.36 |
| PI,max cmH2O | 35±14.5 | 33±14.5 | 35±15.3 | 2.133 (-0.44–4.71) | 0.11 |
| PE,max cmH2O | 69 (0–173) | 70 (0–160) | 68 (6–189) | -0.350 (-4.56–3.86) | 0.87 |
| Pmo,w cmH2O | 47 (10–194) | 58 (10–218) | 51 (8–239) | -2.400 (-7.55–2.75) | 0.36 |
| SNIP cmH2O | 28±9.2 | 29±11.0 | 29±9.2 | -0.150 (-2.36–2.06) | 0.89 |
Data are expressed as mean±sd or median (range), unless otherwise stated. CI: confidence interval; FVC: forced vital capacity; FEV1: forced expiratory volume in one second; PI,max: maximal inspiratory pressure at mouth; PE,max: maximal expiratory pressure at mouth; Pmo,w: maximal whistle mouth pressure; SNIP: sniff nasal inspiratory pressure. #: refers to difference of means between ventilators, taking into account the effect of period, order of use and baseline data; a p-value <0.05 was considered significant. ¶: n = 19. 1 cmH2O = 0.098 kPa.