Table 4—

Pulmonary function and respiratory muscle strength test results following treatment with standard noninvasive ventilation(NIV) and autotitrating NIV compared with baseline

VariableBaselineStandard NIVAutotitrating NIVDifference (95% CI)p-value#
Subjects n202020
FVC L0.89±0.400.86±0.410.87±0.420.016 (-0.04–0.07)0.54
FEV1 L0.66±0.310.62±0.300.62±0.320.002 (-0.04–0.04)0.93
FEV1/FVC0.77±0.130.83±0.190.79±0.14-0.029 (-0.09–0.03)0.36
PI,max cmH2O35±14.533±14.535±15.32.133 (-0.44–4.71)0.11
PE,max cmH2O69 (0–173)70 (0–160)68 (6–189)-0.350 (-4.56–3.86)0.87
Pmo,w cmH2O47 (10–194)58 (10–218)51 (8–239)-2.400 (-7.55–2.75)0.36
SNIP cmH2O28±9.229±11.029±9.2-0.150 (-2.36–2.06)0.89
  • Data are expressed as mean±sd or median (range), unless otherwise stated. CI: confidence interval; FVC: forced vital capacity; FEV1: forced expiratory volume in one second; PI,max: maximal inspiratory pressure at mouth; PE,max: maximal expiratory pressure at mouth; Pmo,w: maximal whistle mouth pressure; SNIP: sniff nasal inspiratory pressure. #: refers to difference of means between ventilators, taking into account the effect of period, order of use and baseline data; a p-value <0.05 was considered significant. : n = 19. 1 cmH2O = 0.098 kPa.