Baseline lung function data of standard methacholine(MCh) challenge study
| Parameters | Pre-HSCT# | Post-HSCT | |
| 3 months¶ | 12 months+ | ||
| FVC L | 4.78±0.99 | 4.45±0.84§ | 4.55±1.21 |
| % pred | 113±15 | 108±16 | 107±14 |
| FEV1 L | 3.96±0.80 | 3.65±0.75ƒ | 3.72±0.96 |
| % pred | 111±16 | 106±15 | 104±14 |
| FEV1/FVC | 0.81±0.08 | 0.81±0.07 | 0.82±0.08 |
| TLC L | 6.44±1.10 | 6.04±1.0## | 5.99±1.36¶¶ |
| % pred | 104±9 | 100±11 | 98±11 |
| FRC L | 2.93±0.45 | 3.02±0.57 | 3.01±0.83 |
| % pred | 94±6 | 97±11 | 97±20 |
| RV L | 1.56±0.39 | 1.55±0.35 | 1.42±0.48 |
| % pred | 90±19 | 87±16 | 82±22 |
| sGaw L·s−1·cmH2O−1 | 0.21±0.04 | 0.21±0.03 | 0.23±0.04 |
| % pred | 92±14 | 91±10 | 95±16 |
| DL,CO mL·min−1·mmHg−1 | 26.1±6.21 | 19.7±4.89 | 23.2±6.10 |
| % pred for Hb | 90±14 | 75±14++ | 80±16§§ |
| MCh FEV1 | |||
| PD20 log μg | 3.09±0.39 | 3.19±0.37 | 3.23±0.24 |
| Slope units | -0.17±0.10 | -0.15±0.10 | -0.15±0.11 |
Values are expressed as mean±SD. HSCT: haematopoietic stem cell transplantation; FVC: forced vital capacity; % pred: % predicted; FEV1: forced expiratory volume in one second; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume; sGaw: specific airway conductance; DL,CO: diffusing capacity of the lung for carbon monoxide; Hb: haemoglobin; PD20: provocative dose (log-transformed) of MCh causing a 20% fall in FEV1. #: n = 17; ¶: n = 16; +: n = 13; §: p = 0.030; ƒ: p = 0.026; ##: p = 0.0007; ¶¶: p = 0.004; ++: p = 0.0002; §§: p = 0.048 (all versus baseline). 1 L·s−1·cmH2O−1 = 10.2 L·s−1·kPa−1; 1 mL·min−1·mmHg−1 = 0.335 mmol·min−1·kPa−1.