Table 4—

Agreement between various definitions of chronic obstructive pulmonary disease(COPD)

LLN of FEV1/FVC ratioDoctor-diagnosed COPD
Post-bronchodilatorPre-bronchodilatorYesNo
YesNoYesNo
GOLD
 Yes12513612014118243
 No07475968818729
κ coefficient0.577 (0.5162–0.638)0.424 (0.359–0.489)0.06 (0.0169–0.107)
 p-valuep<0.001#p<0.001#p = 0.001#
LLN of FEV1/FVC post-bronchdilator
 Yes88378117
 No9179228855
κ coefficient0.507 (0.434–0.580)0.047 (-0.0157–0.110)
 p-valuep<0.001#p = 0.069
LLN of FEV1/FVC pre-bronchdilator
 Yes9170
 No27802
κ coefficient0.026 (-0.023–0.075)
p-valuep = 0.247
  • Data are presented as n or κ coefficient (95% confidence interval), unless otherwise stated. LLN: lower limit of normal range; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; GOLD: Global Initiative for Chronic Obstructive Lung Disease. #: p<0.05.