Demographic data and short Synacthen test results for study subjects divided according to evidence of adrenal suppression
| Not suppressed | Suppressed | p-value | |
| Subjects n | 30 | 20 | |
| Males | 9 (64.3) | 5 (35.7) | 0.70 |
| Females | 21 (58.3) | 15 (41.7) | |
| Age yrs | 62±2 | 64±3 | 0.661 |
| Number receiving ICS | 17 | 16 | 0.043 |
| FEV1 % pred | 55.3±3.9 | 56.9±4.7 | 0.790 |
| FEV1/FVC | 58.1± 2.5 | 61.7±3.5 | 0.407 |
| KCO % pred | 103.8±4.0 | 110.7±4.7 | 0.272 |
| Basal cortisol nmol·L−1 | 450±9 | 335±19 | <0.001 |
| Incremental cortisol response nmol·L−1 | 199±90 | 141±23 | 0.05 |
| ACTH ng·L−1 | 28.5± 3.4 | 29.8±4.0 | 0.804 |
| Fasting glucose mmol·L−1 | 4.9±0.1 | 5.1±0.4 | 0.575 |
| Systolic blood pressure mmHg | 145±4.2 | 145±5.5 | 1.0 |
| Diastolic blood pressure mmHg | 83±2.3 | 82±1.9 | 0.807 |
| Postural hypotension | |||
| 1 min | 8 (26.7) | 7 (35) | 0.53 |
| 3 min | 12 (40) | 6 (30) | 0.47 |
| Anytime | 14 (46.7) | 9 (45) | 0.91 |
| Tiredness | 27 (90) | 20 (100) | 0.27 |
| Generalised weakness | 19 (63.3) | 13 (65) | 0.90 |
| Lack of energy | 25 (83.3) | 18 (90) | 0.69 |
| Weight loss | 10 (33.3) | 8 (40) | 0.69 |
| Nausea | 9 (30) | 10 (50) | 0.15 |
| Vomiting | 2 (6.6) | 5 (25) | 0.42 |
| SGRQ | |||
| Symptoms domain | 47.6±1.9 | 42.9±2.3 | 0.125 |
| Activity domain | 66.8±3.5 | 61.6±5.8 | 0.450 |
| Impact domain | 35.5±3.0 | 40.5±5.0 | 0.404 |
| Total | 47.0±2.5 | 47.3±4.4 | 0.962 |
Data are presented as n (%) or mean±sem, unless otherwise stated. ICS: inhaled corticosteroid; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity; KCO: transfer coefficient of the lung for carbon monoxide; ACTH: adrenocorticotropic hormone; SGRQ: St George’s Respiratory Questionnaire.