Table 2—

Study characteristics

ParameterLung cancerCOPDControl smokers
Subjects n454458488
Males535960
Age yrs69±1066±965±10
Smoking history
 Current smoker354048
 Age started smoking yrs18±417±317±3
 Length of time smoked yrs41±1242±1135±11
 Pack-yrs41±25*47±20*40±19*
 Cigarettes·day−120±1023±924±11
Time since quitting yrs11.4±6.79.8±7.413.9±8.1
History of other exposures
 Work dust63*59*47*
 Work fume414038
 Asbestos23*22*16*
Family history
 COPD333728
 Lung cancer19*11*9*
Lung function
 FEV1 L1.86±0.48*1.25±0.48*2.86±0.68*
 FEV1 % pred73*46*99*
 FEV1/FVC64±13*46±8*78±7*
 Spirometric COPD#57*100*0*
  • Data are presented as % or mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity. #: according to Global Initiative for Chronic Obstructive Lung Disease stage 2. *: p<0.05.