General characteristics and pulmonary function tests in patients with chronic obstructive pulmonary disease grouped according to inspiratory capacity(IC)/total lung capacity (TLC) ratio
| IC/TLC >25% | IC/TLC ≤25% | Difference between means (95% CI) | p-value | |
| Subjects n | 42 | 45 | ||
| Age yrs | 63±7 | 66±10 | -2.8 (-6.6–1.0) | 0.1# |
| BMI kg·m−2 | 27.8 (24.6–31.5) | 24.9 (22.3–26.9) | 2.7 (0.6–4.8) | 0.008¶ |
| FFM kg | 59.0 (50.9–60.8) | 51.9 (41.1–64.2) | 8.1 (1.7–14.5) | 0.004¶,+ |
| FFM index kg·m−2 | 21±3 | 19±4 | 1.8 (0.02–3.6) | 0.04# |
| MMRC | 2 (2–3) | 2 (2–3) | -0.20 (-0.54–0.13) | 0.3¶ |
| 6MWD m | 415±91 | 326±80 | 89 (52–125) | <0.001#,+ |
| Hand grip force kg | 33.5 (26–46) | 26 (20–36) | 8.7 (3.8–13.6) | <0.001¶,+ |
| FEV1 % pred | 36 (30–41) | 30 (26–39) | 3.9 (0.3–7.5) | 0.03¶ |
| FVC % pred | 68±15 | 64±17 | 4.2 (-2.8–11.2) | 0.2# |
| TLC % pred | 119 (97–134) | 132 (126–151) | -16.6 (-26.4– -6.9) | 0.001¶,+ |
Data with a normal distribution are presented as mean±sd and data not normally distributed is presented as median (interquartile range), unless otherwise stated. CI: confidence interval; BMI: body mass index; FFM: fat-free mass; MMRC: Modified Medical Research Council dyspnoea scale; 6MWD: 6-min walk distance; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity. #: comparisons performed using the unpaired t-test; ¶: comparisons performed using the Mann–Whitney test; +: significant values after using Bonferroni corrections to adjust for multiple comparison.