Table 4—

Appropriateness of empirical antibiotic treatment and normalisation patterns of C-reactive protein (CRP)

Unknown aetiologyPatients with established aetiology
Received appropriate antibiotic treatmentReceived inappropriate antibiotic treatmentMean difference# (95% CI)p-value
Subjects152 (52.6)112 (38.8)25 (8.7)
Median CRP values
 Day 0 140.5 (56–293)233.0 (131–358)152 (63–243)
 Day 390.0 (23–153)98.0 (30–168)108.5 (55–215)
 Day 729.0 (12–79)36.0 (18–75)29 (15–92)
Mean decline in CRP
 Day 0–336.3±30.444.5±30.525.2±24.419.3 (6.1–32.5)<0.001
 Day 0–763.1±34.675.5±24.760.4±32.315.1 (1.8–28.5)0.03
  • Data are presented as n (%), median (interquartile range) or mean±sd, unless otherwise stated. CI: confidence interval. #: the mean difference (95% CI) in per cent decline in CRP among patients with appropriate and inappropriate antibiotic treatment (established aetiology) is displayed.