Table 3—

Methods of treatment of pulmonary hypertension in chronic obstructive pulmonary disease

MethodsReferencesAt least one randomised trial?
LTOT112–116Yes
Nocturnal oxygen therapy117, 118Yes
Medical treatment dedicated to PAH119, 120Yes
Ca2+ channel blockers121No
Urapidil122No
Angiotensin inhibitors123, 124Yes
Inhaled nitric oxide125Yes
Pulmonary rehabilitation126No
LVRS127–130Yes
Lung transplantation131No
  • LTOT: long-term oxygen therapy; PAH: pulmonary arterial hypertension; LVRS: lung volume reduction surgery.