Table 2—

Median baseline C-reactive protein (CRP) values according to aetiology in patients with severe community-acquired pneumonia

SubjectsMedian CRP levelSize of rangeInterquartile range
Streptococcus pneumoniae#55 (19.0)278.0686147–390
Haemophilus influenzae9 (3.1)214.0278168–313
Staphylococcus aureus8 (2.8)187.0299115–330
Chlamydia pneumoniae10 (3.5)115.532857–317
Mycoplasma pneumoniae5 (1.7)49.029927–228
Legionella pneumophila+7 (2.4)247.0286176–421
Enterobacteriaciae§15 (5.2)129.045253–272
Moraxella catarrhalis5 (1.7)64.019749–165
Other pathogensƒ11 (3.8)185.0403117–231
Multiple bacterial pathogens12 (4.2)213.067283–404
Unknown aetiology152 (52.6)140.557656–293
  • #: determined by sputum culture (n = 19), blood culture (n = 24) or urinary antigen test (n = 20), in eight cases S. pneumoniae was determined by multiple tests; : determined by sputum culture (n = 6) or blood culture (n = 2); +: all determined by both serology and urinary antigen test (n = 7); §: Enterobacteriaciae include: Eschericia Coli (n = 6; 2.1%); Klebsiella pneumoniae (n = 4; 1.4%); Proteus mirabilis. (n = 1; 0.3%); Enterobacter spp. (n = 2; 0.7%); Citrobacter spp. (n = 2; 0,7%); ƒ:other pathogens include: P. aeruginosa (n = 2; 0.7%); Streptococcus agalactiae (n =  3; 1.0%); H. parainfluenzae (n = 2; 0.7%); Staphylococcus hominis (n = 1; 0.3%); Proprionibacter acnes (n = 1; 0.3%); Gram-positive spp. (n = 2; 0.7%).