Stable patients | BOS | |||||
No pathogens | Pathogens | p-value# | No pathogens | Pathogens | p-value# | |
Subjects | 23 | 7 | 8 | 6 | ||
Sex M/F | 10/13 | 3/4 | 4/4 | 4/2 | ||
Age yrs | 42 (22–62) | 38 (22–55) | ns | 30 (18–59) | 29 (21–58) | ns |
Days after transplant | 186 (10–1533) | 313 (34–368) | ns | 944 (84–2025) | 410 (89–907) | ns |
Total neutrophils ×104 | 0.2 (0–58.8) | 8.2 (0.1–63.4) | 0.019 | 3.7 (0–92.7) | 3.8 (0.1–204.9) | 0.846 |
Neutrophils % | 1.4 (0–26.6) | 46.6 (1.6–72.4) | 0.003 | 18 (0–91.4) | 22 (2.2–99.6) | 0.699 |
IL-8 pg·mL−1 | 25 (0–2320) | 1664 (45–8759) | 0.001 | 369 (17–3730) | 962 (105–15008) | 0.302 |
HNE ng·mL−1 | 6 (1–733) | 1374 (13–2886) | <0.001 | 95 (2–454) | 51 (13–174) | 0.561 |
Data are presented as n or median (range), unless otherwise stated. M: male; F: female; IL: interleukin; HNE: human neutrophil elastase; ns: nonsignificant. #: Mann–Whitney.