Table 2—

Physiological and inflammatory values for each subject at baseline and on the final visit in the study

Patient
1212345
TreatmentPPLCNLCNLCNLCNLCN
Weeks of trial drug92068464
Prednisone dose mg·day−1
 Baseline2510251010155
 Final150257.510105
FEV1 L
 Baseline2.472.872.313.201.412.543.84
 Final1.692.951.852.971.282.092.96
Blood eosinophils 106 cells·mL−1
 Baseline0.020.40.20.20.20.80.6
 Final0.31.00.20.10.20.10.9
Sputum TCC 106 cells·mL−1
 Baseline9.45.46.24.04.24.64.4
 Final9.12.927.020.4NA7.516.8
Sputum eosinophils %
 Baseline7.00.77.78.710.05.00.0
 Final44.339.316.51.3NA0.343.3
Sputum neutrophils %
 Baseline62.334.760.338.025.341.075.8
 Final38.019.375.894.7NA93.042.7
Serum lidocaine μg·mL−1000.70.20.70.10.2
  • FEV1: forced expiratory volume in one second; TCC: total cell count; NA: not available; P: placebo; LCN: lidocaine–hydrofluoroalkane 134a.