Table 1—

Baseline characteristics

Age yrs5150677042
Duration of asthma yrs7719208
FEV1 % pred5679727597
FEV1/VC %4867675864
ΔFEV1 mL (%)#280 (15)130 (5)200 (14)320 (14)400 (12)
Methacholine PC20 mg·mL−120.96>8NA32
Duration of prednisone treatment yrs72.51973
Other asthma therapies μg·day−1FP 2000, S 100BUD 1600FP 2000, S 100FP 2000FP1000, MONT
  • Spirometry values were recorded post-bronchodilation. FEV1: forced expiratory volume in one second; % pred: % predicted; VC: vital capacity; PC20: provocative concentration causing a 20% fall in FEV1; FP: fluticasone diproprionate; S: salmeterol; BUD: budesonide; MONT: montelukast; NA: not available. #: improvement in FEV1 after 200 μg salbutamol, withholding long- and short-acting β2-agonists for 48 and 8 h, respectively.