Table 4—

Univariate analysis of risk factors for 30-day mortality in community-acquired pneumonia patients

OR (95% CI)p-value
Age <65/≥65 yrs5.03 (3.34–7.56)<0.001
Comorbid condition
 Chronic pulmonary disease1.104 (0.80–1.53)0.560
 Chronic heart disease2.76 (2.01–3.78)<0.001
 Congestive heart failure4.91 (3.56–6.78)<0.001
 Cerebrovascular disease5.91 (4.25–8.22)<0.001
 Other neurological disorder3.86 (2.61–5.69)<0.001
 Chronic liver disease2.98 (1.67–5.29)0.001
 Chronic kidney failure4.22 (2.86–6.22)<0.001
 Diabetes mellitus2.55 (1.83–3.57)<0.001
Nursing home8.00 (5.66–11.30)<0.001
CURB score#2.60 (2.10–3.20)<0.001
Change of antibiotic treatment
 Overall1.30 (0.90–1.83)0.186
 Ineffectiveness2.24 (1.50–3.34)0.001
 Sequential therapy0.46 (0.24–0.94)0.026
 De-escalation0.40 (0.13–1.27)0.159
 Intolerance1.52 (0.46–5.02)0.457
 Resistance0.94 (0.93–0.95)0.258
  • OR: odds ratio; CI: confidence interval; CURB: confusion, urea, respiratory frequency and blood pressure. #: univariate analysis performed as logistic regression; OR and 95% CI shown are per step.