Table 3—

Prevalence of respiratory and allergic symptoms and association with modelled endotoxin exposure in 877 adult agricultural workers, stratified by farm childhood

All subjectsFarm childhood
No#Yes
%OR (95% CI)%OR (95% CI)%OR (95% CI)
Cough symptoms
 Daily cough8.11.29 (1.03–1.62)10.21.10 (0.82–1.48)6.71.58 (1.11–2.25)
 Daily cough with phlegm7.31.60 (1.27–2.03)8.01.40 (1.01–1.93)6.91.84 (1.31–2.58)
 Woken due to cough14.11.36 (1.13–1.64)19.31.18 (0.93–1.50)10.41.67 (1.25–2.25)
SOB and wheezing
 Woken due to SOB3.31.47 (1.05–2.07)4.41.51 (0.99–2.32)2.51.41 (0.82–2.43)
 Wheezing11.41.41 (1.16–1.72)12.81.33 (1.02–1.73)10.41.48 (1.10–1.99)
 Wheezing with SOB7.41.50 (1.18–1.90)8.51.42 (1.04–1.95)6.71.55 (1.09–2.21)
 Wheezing without a cold6.61.60 (1.25–2.05)7.91.70 (1.23–2.36)5.71.44 (0.98–2.12)
Asthma
 Doctor-diagnosed
  Age <18 yrs4.10.79 (0.58–1.10)5.80.84 (0.58–1.24)2.90.62 (0.33–1.19)
  Age ≥18 yrs0.90.99 (0.48–2.03)1.10.95 (0.39–2.31)0.80.90 (0.28–2.82)
 Asthma attack last year0.90.81 (0.41–1.63)1.10.87 (0.36–2.14)0.80.79 (0.26–2.44)
 Current asthma medication use2.30.71 (0.45–1.14)3.00.71 (0.41–1.24)1.80.58 (0.25–1.37)
Allergy
 Any self-reported allergy24.90.82 (0.70–0.96)26.20.75 (0.60–0.93)23.90.89 (0.70–1.12)
 Hay fever10.50.62 (0.49–0.78)13.70.59 (0.44–0.80)8.20.64 (0.43–0.95)
 House-dust allergy10.40.86 (0.69–1.07)12.60.76 (0.57–1.00)8.81.03 (0.74–1.45)
  • Data are presented as the odds ratio (OR) for an interquartile range (exp1.45 = factor 4.3) increase in modelled endotoxin exposure with 95% confidence interval (CI), unless otherwise stated. ORs were adjusted for age, smoking habits, sex and (in unstratified analysis) farm childhood. SOB: shortness of breath. #: n = 366; : n = 511.