Clinical and haemodynamic characteristics of patients#
| Before treatment | After treatment | p-value | |
| WHO functional class | |||
| II | 10 | 22 | |
| III | 30 | 20 | |
| IV | 2 | 0 | |
| 6MWD m | 399±88 | 442±86 | <0.001 |
| Resting haemodynamics | |||
| P̄sa mmHg | 88±12 | 88±15 | 0.804 |
| fC beats·min−1 | 81±11 | 83±11 | 0.156 |
| P̄ra mmHg | 8±5 | 8±4 | 0.625 |
| P̄pa mmHg | 55±13 | 52±14 | 0.038 |
| Ppao mmHg | 8±3 | 9±3 | 0.051 |
| CI L·min−1·m−2 | 2.56±0.69 | 2.85±0.65 | <0.001 |
| SVi mL·m−2 | 32±10 | 35±10 | 0.015 |
| PVRi mmHg·L−1·min·m−2 | 19.4±6.6 | 16.3±6.4 | <0.001 |
| Sv,O2 % | 63±8 | 64±8 | 0.114 |
| Exercise haemodynamics¶ | |||
| P̄pa–CI slope mmHg·L−1·min·m−2 | 21.3±10.9 | 21.5±15.2 | 0.953 |
| Peak P̄pa mmHg | 76±16 | 76±17 | 0.817 |
| Peak CI L·min−1·m−2 | 3.71±1.24 | 4.29±1.26 | <0.001 |
| Isoflow P̄pa mmHg | 73±15 | 66±18 | 0.006 |
| Peak RVSWI g·m·m−2·beat−1 | 27±13 | 30±11 | 0.034 |
Data are presented as n or mean±sd, unless otherwise specified. WHO: World Health Organization; 6MWD: 6-min walking distance; P̄sa: mean systemic arterial pressure; fC: cardiac frequency; P̄ra: mean right atrial pressure; P̄pa: mean pulmonary arterial pressure; Ppao: pulmonary arterial occlusion pressure; CI: cardiac index; SVi: stroke volume index; PVRi: pulmonary vascular resistance index; Sv,O2: mixed venous oxygen saturation; RVSWI: right ventricular stroke work index. #: n = 42; ¶: the workload at peak exercise was 20 W (n = 13), 30 W (n = 13) or 40 W (n = 16) before treatment and 20 W (n = 6), 30 W (n = 15) or 40 W (n = 21) after treatment.