Predictors of quality of life and missed working days on multivariate logistic regression analysis in subjects without a known diagnosis#
| EQ-5D domain¶ | Reference | OR (95% CI) | p-value |
| Mobility 2 | 1 | ||
| FEV1 30–<50% pred | ≥80% pred | 13.8 (2.6–73.9) | 0.0022 |
| FEV1 50–<80% pred | ≥80% pred | 1.8 (1.1–3.0) | 0.0208 |
| Age ≥75 yrs | 45–54 yrs | 3.1 (1.0–9.4) | 0.0428 |
| Activity 2 | 1 | ||
| FEV1 50–<80% pred | ≥80% pred | 2.0 (1.2–3.4) | 0.0062 |
| Age ≥75 yrs | 45–54 yrs | 5.0 (1.5–16.6) | 0.0089 |
| Daily cigarettes ≥21 | 2–20 | 2.1 (1.1–3.9) | 0.0198 |
| Anxiety 2 | 1 | ||
| Female sex | Male | 2.1 (1.7–2.7) | <0.0001 |
| Anxiety 3 | 1 | ||
| Female sex | Male | 3.7 (2.3–6.0) | <0.0001 |
| Pain 2 | 1 | ||
| FEV1 50–<80% pred | ≥80% pred | 1.4 (1.1–1.9) | 0.0190 |
| Age ≥75 yrs | 45–54 yrs | 1.9 (1.1–3.4) | 0.0325 |
| Pain 3 | 1 | ||
| Age 55–64 yrs | 45–54 yrs | 3.0 (1.4–6.4) | 0.0048 |
| Age 65–74 yrs | 45–54 yrs | 3.6 (1.0–12.2) | 0.0432 |
| Age ≥75 yrs | 45–54 yrs | 4.4 (1.1–18.4) | 0.0414 |
| FEV1 50–<80% pred | ≥80% pred | 2.1 (1.1–4.0) | 0.0212 |
| Missed working day ≥1+ | |||
| Chronic bronchitis | None | 6.0 (2.8–12.7) | <0.0001 |
EQ-5D: European quality of life five-dimension questionnaire; OR: odds ratio; CI: confidence interval; FEV1: forced expiratory volume in one second; % pred: % predicted. #: of chronic obstructive pulmonary disease, asthma or any other predefined comorbid illness (bronchiectasis or chronic heart failure); ¶: no independent predictor was found for mobility class 3 or activity class 3; +: analysis restricted to those aged <65 yrs (n = 1,310).