Table 1—

Anthropometric, sleep and metabolic parameters

CharacteristicsHVOSAp-value
Subjects n716
Age yrs47.1±5.548.7±12.6ns
BMI kg·m−223.8±1.926.8±2.8<0.05
Fasting glucose mmol·L−14.6±0.24.9±0.3<0.01
HOMA0.9±0.81.9±1.3<0.05
Cholesterol g·L−1
 Total2±0.32.2±0.3<0.05
 LDL1.1±0.31.5±0.3ns
 HDL0.6±0.20.5±0.1ns
Triglycerides g·L−11.2±0.61.4±0.6ns
Serum albumin g·L−143.6±2.443.1±2.9ns
Urinary isoprostaglandins mg·nmol−1 of creatinine7.7±313.6±110.14
Blood pressure mmHg
 Systolic123.6±11.8135.3±10.60.02
 Diastolic76.4±8.580.1±10.4ns
AHI events·h−14.4±3.733.7±18<0.001
Sa,O2 mean %95.1±193.5±2.20.05
Sa,O2 min %88.7±2.383.5±7.5<0.05
Time# Sa,O2<90%0.1±1.39.8±19.4ns
hsCRP mg·L−10.6±0.22.6±2.6<0.05
  • Data are presented as mean±sd, unless otherwise stated. HV: healthy volunteers; OSA: obstructive sleep apnoea; BMI: body mass index; HOMA: homeostasis model assessment; LDL: low-density lipoprotein; HDL: high-density lipoprotein; AHI: apnoea/hypopnoea index; Sa,O2: arterial oxygen saturation; hsCRP: high-sensitivity C-reactive protein; ns: nonsignificant. #: percentage of total sleep time.