Table 2—

Dog ownership and contact during childhood and sensitisation to dog, mixed pollen and inhalant allergens at age 6 yrs#

Sensitisation outcome at age 6 yrs
DogMixed pollenInhalant allergen
Dog ownership
 LISA
  At age 1 yrs0.9 (0.4–2.6)0.6 (0.1–1.2)0.6 (0.3–1.0)
  At age 6 yrs1.0 (0.2–2.8)0.7 (0.3–1.3)0.8 (0.4–1.3)
  Up to age 6 yrs0.5 (0.2–1.4)0.6 (0.4–1.0)0.6 (0.3–0.9)
 GINI noninterventional
  At age 1 yrs1.7 (0.0–4.2)0.5 (0.8–1.1)0.5 (0.2–0.9)
  At age 6 yrs1.9 (0.6–4.1)1.1 (0.2–1.8)0.8 (0.5–1.3)
  Up to age 6 yrs1.9 (0.8–3.9)0.8 (0.7–1.3)0.8 (0.5–1.2)
 GINI interventional
  At age 1 yrs0.7 (0.0–1.9)0.5 (0.4– 1.0)0.5 (0.3–0.9)
  At age 6 yrs1.2 (0.2–2.7)0.6 (0.2–1.0)0.6 (0.3–0.9)
  Up to age 6 yrs1.0 (0.4–2.1)0.5 (0.3–0.9)0.5 (0.3–0.8)
 Total+
  At age 1 yrs1.1 (0.5–1.9)0.6 (0.4–0.8)0.5 (0.4–0.7)
  At age 6 yrs1.4 (0.8–2.3)0.8 (0.6–1.1)0.7 (0.5–1.0)
  Up to age 6 yrs1.1 (0.7–1.8)0.7 (0.5–0.9)0.6 (0.5–0.8)
Dog contact
 LISA
  Only at age 1 yr§1.4 (0.4–2.9)1.0 (0.4–1.5)0.9 (0.6–1.2)
  Only up to age 4 yrs§0.8 (0.7–1.7)0.9 (0.7–1.3)0.8 (0.6–1.1)
 GINI noninterventional
  Only at age 1 yr§0.9 (0.4–1.9)0.8 (0.3–1.3)1.0 (0.7–1.4)
  Only up to age 4 yrs§0.7 (0.4–1.8)0.8 (0.6–1.3)1.2 (0.8–1.8)
 GINI interventional
  Only at age 1 yr§0.9 (0.4–1.7)1.0 (0.6–1.5)0.9 (0.6–1.3)
  Only up to age 4 yrs§1.2 (0.4–2.2)0.9 (0.7–1.3)0.9 (0.6–1.3)
 Total+
  Only at age 1 yr§1.0 (0.7–1.6)1.0 (0.8–1.2)0.9 (0.7–1.1)
  Only up to age 4 yrs§0.9 (0.6–1.4)0.9 (0.7–1.1)0.9 (0.8–1.1)
  • Data are presented as odds ratio (95% confidence intervals). LISA: Influences of Lifestyle Related Factors on the Human Immune System and Development of Allergies in Childhood; GINI: German Infant Nutritional Intervention Programme. #: adjusted for sex, study centre, parental educational level and parental allergy; : specific immunoglobulin E titre >0.35 kU·L−1 to tested allergen; +: additionally adjusted for studies; §: dog owners were excluded.