Table 2—

Total area and smooth muscle area of biopsies from nonasthmatic and asthmatic subjects used for cyclin D1 immunohistochemistry

NonasthmaticMild asthmaModerate asthmaSevere asthma
Subjects n3438514
Total biopsy area mm20.22 (0.17–0.34)0.28 (0.15–0.36)0.33 (0.16–0.33)0.26 (0.17–0.50)
Smooth muscle area %0.7 (0–5.7)3.0 (0–7.8)1.1 (0–20.5)19.9 (3.8–34.9)**
  • Data are presented as median (interquartile range), unless otherwise stated. **: p<0.01 compared with nonasthmatic (Kruskal–Wallis test followed by Dunn’s post hoc test).