Demographic data for subjects from the Melbourne Epidemiological Study of Childhood Asthma cohort from whom biopsies were obtained for immunohistochemistry and cell culture
| Immunohistochemistry | Cell culture | |||||
| Nonasthmatic | Mild asthma# | Moderate asthma# | Severe asthma# | Nonasthmatic | Asthmatic¶ | |
| Subjects (M/F) n | 34 (21/13) | 38 (24/14) | 5 (4/1) | 14 (6/8) | 22 (15/7) | 25+ (16/9) |
| FEV1 % pred | 104 (96–115) | 102 (93–108) | 67 (66–71)** | 60 (57–74)*** | 101 (98–110) | 97 (85–115) |
| Atopic | 65 | 85 | 100 | 71 | 68 | 77 |
| Current smokers | 71 | 49§ | 67 | 0ƒ | 82 | 52 |
| Current treatment | ||||||
| β2-adrenoceptor agonists | 0 | 74 | 100 | 100 | 0 | 76 |
| Inhaled steroids | 0 | 37 | 80 | 100 | 0 | 40 |
| Oral steroids | 0 | 0 | 0 | 64 | 0 | 0 |
Data presented as median (interquartile range) or %, unless otherwise stated. M: male; F: female; FEV1: forced expiratory volume in one second; % pred: % predicted. #: classified using Global Initiative for Asthma guidelines; ¶: all asthmatics were combined for analysis since few biopsies from moderate or severe asthmatics were available for culture; +: 20 mild, four moderate and one severe asthmatic; §: smoking status unknown in 3%; ƒ: smoking status unknown in 14%. **: p<0.01; ***: p<0.001 for Kruskal–Wallis test followed by Dunn’s post hoc test.