Table 3—

Stroke volume(SV) at rest and during exercise measured using magnetic resonance imaging before and after treatment with sildenafil

Healthy controls#COPD patients
Before treatment with sildenafilAfter 3-month treatment with sildenafil
Cardiac frequency beats·min−171±896±12+78±13*94±15+79±1099±8+
SV mL·beat−181±22101±28+62±12*70±15*,+64±1273±21+
Cardiac output L·min−15.7±1.59.6±2.6+5.1±1.46.7±2.0*,+5.3±1.47.3±2.2+
  • Data are presented as mean±sd. COPD: chronic obstructive pulmonary disease. #: n = 8; : n = 15. *: p<0.05 versus healthy controls; +: p<0.05 versus rest in same treatment.