Table 2—

Unadjusted and adjusted odds ratios for wheezing phenotypes according to Composite Household Chemical Exposure z-score, and stratified for atopy

UnadjustedAdjustedp-value
nOR (95% CI)All#NonatopicAtopic
nOR (95% CI)nOR (95% CI)nOR (95% CI)
Subjects716259873240908
Never wheezed40721.00+35221.00+19711.00+4331.00+
Early-onset transient19091.11 (1.05–1.18)15011.07 (0.99–1.14)8961.06 (0.97–1.16)1880.99 (0.81–1.22)0.8
Early-onset persistent4131.37 (1.24–1.53)3171.21 (1.08–1.38)1051.41 (1.13–1.76)1060.89 (0.69–1.15)0.001
Intermediate-onset transient4521.12 (1.01–1.24)2561.13 (1.01–1.28)1931.11 (0.94–1.31)631.13 (0.84–1.52)0.7
Intermediate-onset persistent1491.08 (0.91–1.29)1291.11 (0.91–1.36)351.47 (1.02–2.13)560.82 (0.59–1.13)0.004
Late-onset1670.98 (0.83–1.16)1401.07 (0.88–1.29)401.69 (1.19–2.41)620.85 (0.63–1.16)0.006
  • Data are presented as odds ratio (95% confidence interval (CI)) unless otherwise stated. OR: odds ratio. #: Adjusted for overcrowding in home, highest maternal education level, housing tenure, sex, exposure to environmental tobacco smoke, maternal history of asthma, maternal parity, maternal age at delivery, smoking during pregnancy, month of completion of chemicals questionnaire and maternal hours worked outside home; : for interaction; +: never wheezed was used as the reference value.