Table 1—

General characteristics and lung function data

COPDHealthy controls
At baselineAfter sildenafil treatment
Subjects n158
Male/female n9/65/3
Age yrs65±2#66±3
Smoking pack-yrs61±11#
BMI kg·m−224±4#23±2
VC % pred100±2699±19118±22
FEV1 % pred49±2446±18109±16
FEV1/VC % pred38±1637±1772±6
TLC % pred125±16124±17103±9
DL,CO % pred48±1646±1794±12
  • Data are presented as mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease; BMI: body mass index; VC: vital capacity; % pred: % predicted; FEV1: forced expiratory volume in one second; TLC: total lung capacity; DL,CO: diffusing capacity of the lung for carbon monoxide. #: data after sildenafil treatment were not significantly different to baseline data.