Table 2—

Characteristics of patients on day of ventilator-associated pneumonia (VAP) suspicion

VAPp-value
NonsuspectedNonconfirmedConfirmed
Subjects n24119
Previous antibiotics days2 (0–3)2 (0–2.5)1 (0–2)0.68
Presence of SIRS15 (62.5)9 (81.8)9 (100)0.072
APACHE II17 (11.5–20.5)17 (14.5–22)21 (20–24)0.18
APS11.5 (8–17)14 (10–19)16 (15–19)0.078
SOFA5 (3–7.5)7 (6–9.5)9 (8–10)0.003
CPIS2 (1–4)6 (5–7)7 (6–8)<0.001
Temperature °C37.4 (36.5–38)38.3 (38–38.4)37 (36–39.4)0.11
Leukocytes 109 cells·L−19.7 (8.0–13.4)10.4 (7.5–14.0)12.4 (10.3–17.7)0.44
Pa,O2/FI,O2 mmHg291 (211–373)210 (181–284)200 (166–229)0.042
Serum CRP mg·dL−17.8 (5.2–11.8)13.3 (11.7–17.1)19.69 (11–20.4)0.004
Serum procalcitonin ng·mL−10.21 (0.09–0.50)0.76 (0.31–0.93)3.86 (2.99–11.30)<0.001
BAL CRP mg·mL−10.42 (0.18–1.03)1.9 (1.67–2.22)0.091
BAL procalcitonin ng·mL−10.08 (0.04–0.19)0.07 (0.04–0.13)0.20
  • Data are presented as median (interquartile range) and n (%) unless otherwise stated. VAP: ventilator-associated pneumonia; SIRS: Systemic Inflammatory Response Syndrome; APACHE: Acute Physiology And Chronic Health Evaluation score; APS: Acute Physiology Score; SOFA: Sepsis-related Organ Failure Assessment; CPIS: Clinical Pulmonary Infection Score; BAL: bronchoalveolar lavage; CRP: C-reactive protein. 1 mmHg = 0.133 kPa.