Characteristics of patients on day of ventilator-associated pneumonia (VAP) suspicion
| VAP | p-value | |||
| Nonsuspected | Nonconfirmed | Confirmed | ||
| Subjects n | 24 | 11 | 9 | |
| Previous antibiotics days | 2 (0–3) | 2 (0–2.5) | 1 (0–2) | 0.68 |
| Presence of SIRS | 15 (62.5) | 9 (81.8) | 9 (100) | 0.072 |
| APACHE II | 17 (11.5–20.5) | 17 (14.5–22) | 21 (20–24) | 0.18 |
| APS | 11.5 (8–17) | 14 (10–19) | 16 (15–19) | 0.078 |
| SOFA | 5 (3–7.5) | 7 (6–9.5) | 9 (8–10) | 0.003 |
| CPIS | 2 (1–4) | 6 (5–7) | 7 (6–8) | <0.001 |
| Temperature °C | 37.4 (36.5–38) | 38.3 (38–38.4) | 37 (36–39.4) | 0.11 |
| Leukocytes 109 cells·L−1 | 9.7 (8.0–13.4) | 10.4 (7.5–14.0) | 12.4 (10.3–17.7) | 0.44 |
| Pa,O2/FI,O2 mmHg | 291 (211–373) | 210 (181–284) | 200 (166–229) | 0.042 |
| Serum CRP mg·dL−1 | 7.8 (5.2–11.8) | 13.3 (11.7–17.1) | 19.69 (11–20.4) | 0.004 |
| Serum procalcitonin ng·mL−1 | 0.21 (0.09–0.50) | 0.76 (0.31–0.93) | 3.86 (2.99–11.30) | <0.001 |
| BAL CRP mg·mL−1 | 0.42 (0.18–1.03) | 1.9 (1.67–2.22) | 0.091 | |
| BAL procalcitonin ng·mL−1 | 0.08 (0.04–0.19) | 0.07 (0.04–0.13) | 0.20 | |
Data are presented as median (interquartile range) and n (%) unless otherwise stated. VAP: ventilator-associated pneumonia; SIRS: Systemic Inflammatory Response Syndrome; APACHE: Acute Physiology And Chronic Health Evaluation score; APS: Acute Physiology Score; SOFA: Sepsis-related Organ Failure Assessment; CPIS: Clinical Pulmonary Infection Score; BAL: bronchoalveolar lavage; CRP: C-reactive protein. 1 mmHg = 0.133 kPa.