Table 3—

Baseline spirometric parameters and severity of chronic obstructive pulmonary disease by bronchodilator responsiveness at baseline

ΔFEV1 ≥12% and ≥200 mLΔFEV1 ≥15%ΔFEV1 ≥10% pred
ResponsivePoorly responsiveResponsivePoorly responsiveResponsivePoorly responsive
FEV1 % pred
 Pre-bronchodilator38.5±10.540.3±13.436.3±10.645.2±12.238.8±10.0*39.7±13.0
 Post-bronchodilator50.6±11.2044.0±13.347.4±12.447.9±13.152.6±10.344.4±13.0
GOLD stage %
 Stage II: moderate56.035.445.748.162.736.3
 Stage III: severe40.649.545.942.536.050.2
 Stage IV: very severe3.315.28.49.41.313.5
 p-value#<0.0001<0.001<0.0001
  • Data are presented as mean±sd, unless otherwise indicated. Δ: change; FEV1: forced expiratory volume in one second; % pred: % predicted; GOLD: Global Initiative for Chronic Obstructive Lung Disease. #: across all GOLD stages shown (versus poorly responsive). *: p<0.05; : p<0.0001 versus poorly responsive patients.