Table 2—

Patient characteristics by bronchodilator responsiveness at baseline

ΔFEV1 ≥12% and ≥200 mLΔFEV1 ≥15%ΔFEV1 ≥10% pred
ResponsivePoorly responsiveResponsivePoorly responsiveResponsivePoorly responsive
Patients3103 (53.9)2653 (46.1)3776 (65.6)1980 (34.4)2224 (38.6)3532 (61.4)
Age yrs64.0±8.4#65.1±8.464.5±8.564.4±8.564.5±8.664.5±8.4
Males79.2#69.273.8*76.372.675.9
BMI kg·m−226.1±5.0*25.7±5.225.8±5.0#26.3±5.226.1±5.025.9±5.1
Current smokers30.730.528.9***33.830.430.7
Smoking history pack-yrs50.0±28.9#47.1±26.549.4±28.3*47.3±27.049.6±28.9*48.1±27.2
Duration of COPD yrs9.7±7.410.0±7.99.8±7.69.9±7.99.6±7.39.9±7.9
SGRQ total score44.4±16.8#47.7±17.345.8±16.746.1±17.744.0±16.8#47.1±17.2
  • Data are presented as n (%), percentage or mean±sd. Δ: change; FEV1: forced expiratory volume in one second; % pred: % predicted; BMI: body mass index; COPD: chronic obstructive pulmonary disease; SGRQ: St George’s Respiratory Questionnaire. *: p<0.05; ***: p<0.001; #: p<0.0001 versus poorly responsive patients.