Table 1—

Characteristics of subjects# with pneumonia by use of statin and/or angiotensin-converting enzyme (ACE) inhibitors versus nonuse of either medication

VariablesUse of statins and/or ACE inhibitorsNonusersp-value
Subjects37284924
Age yrs74.6±5.975.7±6.3<0.001
Males3669 (98)4858 (99)0.4
Race
 White2941 (79)3869 (79)
 Black491 (13)680 (14)
 Hispanic206 (6)256 (5)
 Other/unknown90 (2)119 (2)0.8
Married2181 (59)2523 (51)<0.001
Charlson comorbid conditions
 Myocardial infarction1115 (30)687 (14)<0.001
 CHF2184 (59)1552 (32)<0.001
 PVD1138 (31)1013 (21)<0.001
 Stroke1322 (35)1356 (28)<0.001
 Chronic lung disease2689 (72)3457 (70)0.05
 Peptic ulcer547 (15)678 (14)0.2
 Rheumatologic disease202 (5)273 (6)0.8
 Mild liver disease60 (2)101 (2)0.1
 Diabetes1767 (47)1268 (26)<0.001
 Dementia351 (9)663 (14)<0.001
 Diabetes with complications797 (21)417 (8)<0.001
 Moderate liver disease18 (0.5)34 (1)0.2
 Hemiplegia171 (5)227 (5)0.9
 Renal disease485 (13)429 (9)<0.001
 Any malignancy1436 (39)2088 (42)<0.001
 Metastatic solid tumour283 (8)542 (11)<0.001
  • Data are presented as n, mean±sd or n (%). CHF: congestive heart failure; PVD: peripheral vascular disease. #: n = 8,652.