Characteristics of subjects# with pneumonia by use of statin and/or angiotensin-converting enzyme (ACE) inhibitors versus nonuse of either medication
Variables | Use of statins and/or ACE inhibitors | Nonusers | p-value |
Subjects | 3728 | 4924 | |
Age yrs | 74.6±5.9 | 75.7±6.3 | <0.001 |
Males | 3669 (98) | 4858 (99) | 0.4 |
Race | |||
White | 2941 (79) | 3869 (79) | |
Black | 491 (13) | 680 (14) | |
Hispanic | 206 (6) | 256 (5) | |
Other/unknown | 90 (2) | 119 (2) | 0.8 |
Married | 2181 (59) | 2523 (51) | <0.001 |
Charlson comorbid conditions | |||
Myocardial infarction | 1115 (30) | 687 (14) | <0.001 |
CHF | 2184 (59) | 1552 (32) | <0.001 |
PVD | 1138 (31) | 1013 (21) | <0.001 |
Stroke | 1322 (35) | 1356 (28) | <0.001 |
Chronic lung disease | 2689 (72) | 3457 (70) | 0.05 |
Peptic ulcer | 547 (15) | 678 (14) | 0.2 |
Rheumatologic disease | 202 (5) | 273 (6) | 0.8 |
Mild liver disease | 60 (2) | 101 (2) | 0.1 |
Diabetes | 1767 (47) | 1268 (26) | <0.001 |
Dementia | 351 (9) | 663 (14) | <0.001 |
Diabetes with complications | 797 (21) | 417 (8) | <0.001 |
Moderate liver disease | 18 (0.5) | 34 (1) | 0.2 |
Hemiplegia | 171 (5) | 227 (5) | 0.9 |
Renal disease | 485 (13) | 429 (9) | <0.001 |
Any malignancy | 1436 (39) | 2088 (42) | <0.001 |
Metastatic solid tumour | 283 (8) | 542 (11) | <0.001 |
Data are presented as n, mean±sd or n (%). CHF: congestive heart failure; PVD: peripheral vascular disease. #: n = 8,652.