Table 1—

Clinical and haemodynamic data at the time of diagnosis of pulmonary arterial hypertension

Clinical dataAll casesIncident casesPrevalent casesp-value#
Subjects n57882496
Age yrs48±14 (21–83)51±14 (21–79)48±14 (21–83)0.063
WHO functional class III–IV8083760.19
Exercise capacity METs3.5±33.6±1.83.5±2.00.87
Haemodynamic data
 mRAP mmHg11±710±711±70.037
 mPAP mmHg52±1451±1252±140.30
 PCWP mmHg10±410±410±40.89
Cardiac index L·min−1·m−22.3±0.92.4±0.82.2±0.90.07
PA,O2 saturation58±1261±1057±120.015
PVR Woods unit12.5±7.311±513±70.027
Acute vasodilator responders4.
 Connective tissue disease304028
 Congenital heart disease111310
 Portal hypertension797
  • Data are presented as %, mean±sd or mean±sd (range), unless otherwise stated. WHO: World Health Organization; METs: metabolic equivalents; mRAP: mean right atrial pressure; mPAP: mean pulmonary artery pressure; PCWP: pulmonary capillary wedge pressure; PA,O2: alveolar oxygen partial pressure; PVR: pulmonary vascular resistance. #: comparisons are for incident versus prevalent cases of pulmonary arterial hypertension.